A possible role of prostaglandins in guinea-pig isolated ileum contractions to serotonin
Identifieur interne : 003951 ( Main/Exploration ); précédent : 003950; suivant : 003952A possible role of prostaglandins in guinea-pig isolated ileum contractions to serotonin
Auteurs : J. P. Famaey [Belgique] ; J. Fontaine [Belgique] ; I. Seaman [Belgique] ; J. Reuse [Belgique]Source :
- Prostaglandins [ 0090-6980 ] ; 1977.
English descriptors
- Teeft :
- Alclofenac, Antiinflammatory, Antiinflammatory drugs, Bufexamac, Cerebral ventricles, Clopirac, Direct effect, Flufenamic, High concentrations, Ileum, Ileum contractions, Indomethacin, July, Longitudinal muscle, Mefenamic, Mefenamic acids, Niflumic, Niflumic acid, Nsaid, Other experiments, Pgel, Phenylbutazone, Prostaglandin, Second column, Serotonin, Small amounts, Steroidal antiinflammatory drugs, Submaximal contractions.
Abstract
Abstract: Nine non-steroidal antiinflammatory drugs have been tested for their effect on contractions to serotonin of the guinea-pig isolated ileum. They exert a potent inhibition which is totally reversible by washing out the drugs. It is also well reversed by the addition of small amounts of PGE1 to the bath. It is concluded that prostaglandins exert a role in these contractions to serotonin which is probably specific as well as non specific.
Url:
DOI: 10.1016/0090-6980(77)90160-5
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Abstract: Nine non-steroidal antiinflammatory drugs have been tested for their effect on contractions to serotonin of the guinea-pig isolated ileum. They exert a potent inhibition which is totally reversible by washing out the drugs. It is also well reversed by the addition of small amounts of PGE1 to the bath. It is concluded that prostaglandins exert a role in these contractions to serotonin which is probably specific as well as non specific.</div>
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